ISSN 1738-6217 (Print)
 
 
 
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Abstract

J Kor Soc Ster Func Neurosurg. 2018 14(1): 10-13
ⓒ Journal of the Korean Society of Stereotactic and Functional Neurosurgery
    
 
Fractionated Radiosurgical Hypophysectomy for Refractory Pain in Patient with Recurrent Glioblastoma Multiforme
Mi Sun Kim, MD2, Je Beom Hong, MD1, Joopyung Kim, MD, PhD1
1Department of Neurosurgery, CHA Bundang Medical Center, CHA University, Seongnam, Korea 2Department of Radiation Oncology, CHA Bundang Medical Center, CHA University, Seongnam, Korea
 

Intractable cancer pain was apparently managed with hypophysectomy more than five decades ago. However, the procedure was associated with serious postoperative complications including panhypopituitarism, diabetes insipidus, chemical meningitis, visual dysfunction, and hypothalamic insult. As an alternative to surgical or chemical interventions, radiosurgical hypophysectomy has been used to control intractable cancer pain without serious complications. However, in a 50-year-old patient treated with 60Gy concurrent chemoradiotherapy and Gamma knife radiosurgery for recurrent glioblastoma multiforme, the adverse effects of re-irradiation as well as pain control were minimized using fractionated radiosurgical hypophysectomy.
 
Key words : Fractionated radiosurgical hypophysectomy, Recurrent glioblastoma multiforme, Opioid-refractory pain.
중심단어 : Fractionated radiosurgical hypophysectomy, Recurrent glioblastoma multiforme, Opioid-refractory pain.
 
 
  
 
 
 

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